Mesothelioma Cancer

by Peter Nisbet

There are various types of mesothelioma but asbestos lung mesothelioma is an asbestos-induced cancer of the mesothelium of the lung, more familiarly known as the pleura, which is the external lining of the lung.

Many of the major organs of the body have a mesothelium, that of the heart being called the pericardium and of the heart the peritoneum. However, it is with the pleura that we are concerned here, and the symptoms of asbestos lung mesothelioma are what you would expect: coughing, discomfort in the chest cavity and eventual pain.

Before we come to possible treatments and palliative care, let’s have a look at what causes it and why we are still seeing new cases today after asbestos was banned for construction use in the 1970s.

Asbestos comes in several forms, the most dangerous thought to be crocidolite, commonly known as blue asbestos. This form of asbestos is in a highly fibrous form, and it is the inhalation and ingestion of these fibers that cause the problem. They tend to remain in the body for a considerable period of time and it can take up to 40 ��” 45 years before the symptoms of mesothelioma begin to appear, though some people contract it in their 30s.

To complicate the situation, it is not only asbestos that causes the symptoms, but any fibrous silicate, which it is why some compensation cases are not as cut and dry as they could be. To add to this complication, smoking adds to the possibility of cancer and it is argued that many patients would not have contracted mesothelioma had they not smoked.

This is not only an argument made by solicitors in court, but has been established by statistics. It is pretty certain that smokers have a greater tendency of contracting asbestos lung mesothelioma than non-smokers, since attorneys for the employers have used this as a reason for having the otherwise high compensation significantly reduced.

There is a popular misconception that mesothelioma is caused by asbestos, but it is just a misconception. Lung cancer is mesothelioma, and in the USA 80% of mesothelioma cases are caused by smoking. That is an indisputable fact. In order to prove the intervention of asbestos in a case, therefore, not only would the patients have to prove that they had worked with asbestos, but also not to have smoked. Had they smoked, then the award could be greatly reduced.

The term “asbestos lung mesothelioma” is therefore a correct one because that form of the disease to which we are referring is caused by asbestos, and not smoking, is of the pleura of the lung and not of the pericardium or peritoneum, and is mesothelioma.

Its treatment is largely palliative, or intended to ease suffering, because the prognosis is fairly grim. Only about 20% of cases live to 5 years after diagnosis, with most surviving only one year, though much depends on how far the condition had developed by the time it was diagnosed. Chemotherapy and radiation treatment are used, but not successfully, and various degrees of surgery are also used. Removal of the affected lung, pericardium and half the diaphragm is the most major of these, and even that only extends life to a maximum of around five years from diagnosis.

There are new treatments being tested, but all treatment is expensive, and a good attorney is likely necessary to secure the compensation to pay for these. Ultimately hospice care will be required and again compensation money should be kept back for this. Ultimately, in spite of all the treatment given, it is palliative care that will make the last days of the patient bearable, as will the help and support of the family, and this is what compensation can fund.

About the Author
More information on this disease can be obtained from Pete’s webpage Asbestos Lung Mesothelioma where more detail is given of possible treatment.

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by James F. Howell

Mesothelioma is a form of cancer caused by exposure to asbestos. Over time, cancerous cells develop in the mesothelium, a protective lining that covers most of the body’s internal organs. Only after several decades do symptoms begin to show, and often because of this delay, by the time mesothelioma is diagnosed it is too late for treatment to be effective.

Mesothelioma is rare, with a rate of infection of only 15 per 1,000,000 in the United States in 2004. It is most often found in individuals who encounter asbestos on the job, such as shipyard workers, people who work in asbestos mines and mills, producers of asbestos products, workers in the heating and construction industries, and other tradespeople.

There are three primary areas mesothelioma can develop, the lining of the lungs and chest cavity known as the pleura, the lining of the abdominal cavity called the peritoneum, or the sac surrounding the heart called the pericardium. Each form of mesothelioma cancer has its own specific symptoms, but there are many symptoms that can be found in all of them. Such symptoms include coughing, fever, shortness of breath, chest or abdominal pain, and fatigue.

Because the symptoms of mesothelioma are so general, it can be very difficult to diagnose the disease. This, combined with such a long delay before symptoms begin to develop often means that little can be done to help the patient. The most common forms of treatment are radiation, chemotherapy, and sometimes surgery. Unfortunately however, these treatments have been unable to increase the survival rate of mesothelioma victims beyond a few months.

About the Author
James Howell is a freelance writer and researcher. Find out more about Mesothelioma Cancer.

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If you ask whether mesothelioma cancer could infect you easily in your workplace I could answer yes right now. Maybe you should already knew what mesothelioma is by reading this article. But if you didn’t I will give you quick brief now.

Mesothelioma is uncommon form of cancer, usually attack the pleura (the lining of the lung and chest cavity) or the peritoneum (the lining of the abdomen). Mesothelioma cancer caused by prolonged or persistent exposure to asbestos.

Unbelievably but true, recent studies showed that It is believed that even insignificant exposure to asbestos in environments such as asbestos mills, mines, shipping yards, some older Navy ships or even patient’s homes can result in mesothelioma cancer.

Now you know that the main reason for mesothelioma cancer is asbestos. Asbestos is the single biggest work place killer today. People who have worked with the material are at serious risk from developing lung cancer, asbestosis and mesothelioma, fatal respiratory illnesses that debilitate their victims.

Most people who suffer mesothelioma have worked on jobs where they inhaled asbestos particles. You should be extra careful if you are: miners, factory workers, insulation manufacturers, railroad workers, ship builders, gas mask manufacturers, and construction workers, particularly those involved with installing insulation.

Not only you could be infected but your family too. Several studies have shown that family members of people exposed to asbestos at work have an increased risk of developing mesothelioma, because asbestos fibers are carried home on your clothes.

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Mesothelioma is uncommon form of cancer, usually attack the pleura (the lining of the lung and chest cavity) or the peritoneum (the lining of the abdomen). Mesothelioma cancer caused by prolonged or persistent exposure to asbestos. Mesothelioma is extremely dangerous.

First, until this article made there is no medical technique to cure this disease or even to significantly slow its effect. Usually 75% of patients die within 18 months of the first signs of the disease. A Lucky patient could survive for approximately 24 months.

Second, is the long latency period between exposure to asbestos, the cause of the disease. Latency runs 15 to 50 years, meaning that you may have been exposed to asbestos long before the first serious signs of the disease manifest themselves. Recent Studies showed the average reported latency is approximately 35-40 years.

Now the big question is how to protect your family? Considering asbestos used in many building in United States and according to the United States Environmental Protection Agency (EPA), as many as 733,000 schools and public buildings still contain asbestos.

Until now we are able to point to a single root source, asbestos exposure, you should take necessary precautions to avoid contraction of the disease from affecting your family. For example you could contact your children local scholl district now to ensure your children did not exposed to asbestos.

In 1986 Congress passed the Asbestos Hazard Emergency Response Act, which required public and private nonprofit schools to inspect their buildings for asbestos-containing materials. However, recent inspection showed that numerous schools still have not taken the necessary steps to eliminate the potential for asbestos exposure.

You should ask your child’s school district to have a copy of documentation that proper steps have been taken to remove asbestos from building. For more information about the school contractor research via the internet and Better Business Bureau to ensure that the contractor has a good track record. More information about mesothelioma can be found at http://mesothelioma-cancer-center.blogspot.com , one of top blogs about mesothelioma.

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About The Author:

One of Leon Reinhart’s close friend died because of mesothelioma. Since then he has write several article about mesothelioma cancer, mesothelioma treatment, and mesothelioma lawyer which you could find on his blog at http://mesothelioma-cancer-center.blogspot.com. His blog are considered one of top blogs about Mesothelioma Cancer.

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One rare form of cancer is called Mesothelioma, a malignant tumor in the mesothelial tissues of the lungs and the abdomen, arising from the inhalation of asbestos. Its rarity is one of the reasons why a lot of people are not aware of this kind of fatal disease. In fact, many people die of Mesothelioma undiagnosed. Although there is now a growing awareness of the hazards of asbestos to health, still many have not heard of Mesothelioma and thus, have not understood its nature, cause, signs and treatment. Even some physicians find it hard to detect Mesothelioma because its symptoms are akin to other diseases like lung cancer and pneumonia. Furthermore, it takes decades for a patient who was exposed to asbestos to develop Mesothelioma — fifty years, at most.

Being unaware of Mesothelioma poses higher risks since it deters diagnosis and treatment. A person undergoing treatment must know the different stages of the cancer or the extent of the disease. Chances of recovering from Mesothelioma and the kind of treatment depend on the stage of the illness. There are basically two staging systems used for Pleural Mesothelioma (lungs): TNM system and Brighan system. These staging systems are also used in other kinds of cancers; however, the first is commonly used. There is no established method in determining the stage of the Peritoneal Mesothelioma cancer (abdominal) so the TNM system is used.

There are three variables in the TNM system: tumor, lymph nodes and metastasis. In the earliest stage of Mesothelioma, stage I, the malignant Mesothelioma cells start to grow and multiply only one layer of the pleura. The pleura is the membrane that encloses the lungs and lines the wall of the chest cavity. However, there are some instances wherein the pericardium (membrane that covers the heart) and diaphragm cover are already affected. In this case, the cancer patient is still in stage I Mesothelioma.

In the second stage, the two layers of the pleura are already affected by Mesothelioma. Take note, however, that in this stage, only one side of the body is affected. Normally, the pleura produces only small amount of lubricating fluid that allows easy expanding and contracting of the lungs. The excess fluid is absorbed by the blood and the lymph vessels so there’s a balance between the amount of fluid produced and removed. During the second stage Mesothelioma, fluid starts to build up between the membrane of the lungs and the membrane of the chest wall, resulting to pleural effusion. The increase in the volume of fluid produced causes shortness of breath and chest pain. Other Mesothelioma cancer patients experience dry and persistent cough. Diagnosis of the pleural effusion is achieved through a chest x-ray.

Stage III Mesothelioma means that the malignant cells have already spread to the chest wall, esophagus and the lymph nodes on one part of the chest. The patient may suffer severe pain near the parts affected. When not treated immediately or when the Mesothelioma patient doesn’t respond well to medication, the cancer may advance to the fourth stage. The fourth stage Mesothelioma is formidable since at this stage the Mesothelioma cells have penetrated into the bloodstream and other organs in the body like the liver, the bones and the brain. The lymph nodes on the other side of the chest may also be affected by Mesothelioma in stage IV.

Brighan staging system, on the other hand, determines whether the Mesothelioma can be surgically removed or not and whether the lymph nodes are affected or not. In stage I Mesothelioma, the lymph nodes are not yet affected and the patient can still recover through surgery. In stage II, surgery can still be executed but some lymph nodes have already been infiltrated by the cancer cells. In stage III, the heart and chest wall are already affected; thus, surgery is no longer advisable. The lymph nodes in this stage, however, may or may not be affected. In the final stage, stage IV Mesothelioma, cancer cells have already gone to the bloodstream and other parts of the body like the heart, brain, bone and liver. In most cases, a patient who has reached stage IV Mesothelioma only has four to twenty-four months to live.

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Smith Chen is an author and internet marketing consultant.
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Mesothelioma cancer is the growth of malignant cells in mesothelium. This mesothelium lining covers the pleural, peritoneal and pericardial cavities. Pleura is a membrane covering the lungs and it is the most common location where mesothelioma cancer occurs also known as pleural mesothelioma. Peritoneum, the protective covering that lines the abdominal cavity may also develop malignant tumors and cause peritoneal mesothelioma.

Mesothelioma is one of the rarest cancers in the world that is caused only by exposure to asbestos. Its exposure can be direct, by inhalation of asbestos or indirect exposure in which the asbestos particles are inhaled from the clothing, hair, equipment or other articles that were previously exposed to asbestos.

Causes of Mesothelioma
Asbestos is a naturally occurring fibrous mineral that is mined in different parts of the world due to its wide utility in various industries. However, it is a deadly carcinogen too and a mojor cause of mesothelioma and asbestosis.

Asbestos fibers are known to cause cancer of the mesothelium. Asbestos is the fibrous form of several minerals and hydrous silicates of magnesium found under ground. There are 3 types of asbestos, the blue one, the while one and the brown one. Of all these 3 types, the blue one also called amphibole, long and thin in structure is more carcinogenic than white or chrysolite asbestos or the brown one known as amosite.

However, in some cases the brown asbestos has also been found to cause mesothelioma. And it is for this reason that people exposed to asbestos even for a short period are vulnerable to the disease.

Pleural Mesothelioma
Asbestos fibers are very fine and easily make their way to the lungs where they settle down in the parenchyma of the lung and penetrate the pleura that later develops malignant mesothelial plaques.

Pleura, which anchors lungs to the chest cavity, is itself a double-layered membrane. The inner layer called visceral pleura surrounds the lungs, while the outer one, known as parietal pleura, forms the lining of the pleural or chest cavity. The two pleural layers are filled with a fluid that helps them to slide over each other as we breathe. As the disease progresses, the delicate pleural membranes thicken and press the lungs. A fluid secreted by the malignant cells, pleural effusion, may also collect between visceral and parietal pleurae that causes problem in breathing and other complications.

Peritoneum Mesothelioma
The asbestos fibers may also cause cancer in the peritoneum, known as peritoneal mesothelioma. This leads to thickening of the membranes surrounding abdominal organs and collection of a fluid, ascites in the abdominal cavity making it swell.

Though it is yet not clear how peritoneal mesothelioma develops, it is believed that from lungs, the asbestos fibers are transported to abdomen and its organs by the lymphatic system or they may be deposited in the gut through saliva contaminated by the asbestos fibers.

Pericardial Mesothelioma
This is the rarest type of mesothelioma cancer that comprises of only 5% of all the mesothelioma cases. Like other types of mesothelioma cancer, pericardial mesothelioma is also caused by the inhalation of asbestos dust and fibers. The lining of the chest cavity which protects the heart is known as pericardium. It is provided with a natural fluid or mucous that provide continuous lubrication to the heart so that it can work properly and perform its functions.

As the asbestos particles settle further into the lining of the chest or pericardial, the cancer spreads in the body. It destroys the heart tissues and muscles that is very hazardous to life and proves fatal for the patient.

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Mesothelioma is a deadly form of cancer that affects the serous membranes surrounding the major organs of the body i.e. the lungs, heart and the abdominal organs, causing these vital organs to inflate with excessive fluid. This fluid further causes the improper functioning of the organs. The only known cause of this cancerous tumor is asbestos exposure. In this disease, malignant cells are built up in the protective linings (serous membranes) of several internal organs known as mesothelium. Different organs in the abdomen cavity can get affected by mesothelioma because of the presence of the protective linings surrounding them. The most common types of mesothelioma include:

* Pleural Mesothelioma,
* Peritoneal Mesothelioma, and
* Pericardial Mesothelioma.

Pleural Mesothelioma:

Pleural Mesothelioma is a tumor in which the lining of the lungs, or lung pleura, gets affected by malignant cells. The pleura is a soft protective tissue that surrounds the lungs in the chest cavity. It helps the lungs in breathing (respiration) by producing a serous fluid that lubricates the pleural surfaces to avoid the teasing of the lungs against the chest wall. The malignant cells, once entered the pleura, begin to spread and affect the surrounding organs and tissues. This leads to further complications resulting pain and severe symptoms.

Mesothelioma affecting pleura is of two categories:

Diffused or Malignant (Cancerous):
It is the serious form of pleural mesothelioma that affects the pleural lining of the lungs and its surrounding organs.

Localized and Benign (Non-cancerous):
It is the non-cancerous form of mesothelioma, which does not affect all parts of the body except the pleura. However, it constricts the lung causing shortness of breath, and in some severe cases, pneumothorax (lung failure).

Peritoneal Mesothelioma:

Peritoneal Mesothelioma is a tumor of the peritoneum membrane or the abdomen lining, affecting many organs in the abdominal cavity including stomach. This form of mesothelioma cancer is less common than the pleural form but is more aggressive, resulting severe symptoms and short life expectancy. Like many other cancers, peritoneal mesothelioma can also be either malignant or benign.

Pericardial Mesothelioma:

Pericardial or Pericardium Mesothelioma is the rarest form of cancer, counting less than 10% of mesothelioma cases. In this form of cancer, fluid gets accumulated in the sac that encloses the heart. The main cause of this disease is the inhalation of asbestos fibers.

Due to the rarity of this disease, doctors and researchers have not clearly understood how the asbestos fibers enter the heart lining or pericardium. The only logical explanation so far about this form of cancer is the possibility of the asbestos fibers, converted into tiny pieces, transported from the lung into the heart by means of blood circulation. Once the asbestos fibers enter the heart, they expand the tissues in the chest cavity and the pericardium with excessive liquid, disrupting the working of the heart and causing chest pains with breathing disorders.

Each year, approximately 2,000 new cases of mesothelioma are diagnosed. At some point of their lives, the patients of mesothelioma have been exposed to asbestos that later cause the hideous cancer of mesothelioma. If you, at some point of your life, have worked in an asbestos-rich environment or used any asbestos materials, you should contact a mesothelioma doctor for correct diagnosis and best treatment options available.

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Asbestos Cancer Mesothelioma is a malignant disease to take a lot of lifes each year, many people concentrate their effort in to know o find out a cure for this disease, and in other economic aspect of the asbestos, such as money compensation.

However, last researches to point out that a blood test could help screen for pleural mesothelioma by checking the blood for high levels of a protein called osteopontin, because blood esteopontin levels rise dramatically in the early stages of pleural mesothelioma, this kind of cancer is a deadly asbestos related illness.

The pleural mesothelioma is a rare disease of the lining of the lung and chest cavity that is usually cancerous, the cause is asbestos exposure and it could take 15 to 35 years to develop the disease, from the time of asbestos exposure.

The above exposure can be direct with the substance or second-hand with a family member whose clothing or skin carried the asbestos into the home. Obviously in the last case the development of the disease could take more than 35 years.

To say, the pleural mesothelioma was so difficult to detect its in early, high mortality rate and a life expectancy of few months, but with the new blood test there are higher percentage of probabilities to detect this kind of cancer, moreover its can detect or determine other kinds of asbestos related cancer. But in the letter case the findings need further study, other kind of cancer to could be early detected for osteopontin blood test is for instance “Ovarian Cancer”.

So, the earlier to pleural mesothelioma cancer is detected, the better and if you want to know how to do it, a blood test could be very useful in this case, and don�t forget it, “Osteopontin”.
Author: Hector Milla

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Source: http://www.articlealley.com/article_14595_23.html

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Malignant mesothelioma detection, like other cancers, can be accomplished with imaging equipment, such as x-ray machines. But once detected, mesothelioma diagnosis is difficult for a number of reasons. First, there is a very extended time period between the exposure to asbestos and the onset of the disease, sometimes as long as 50 to 60 years. Patients would often not think to tell their doctors about working in an asbestos-related job many years earlier.

Second, the typical symptoms of mesothelioma, shortness of breath and coughing, are also symptoms of many other types of lung problems, both cancerous and non-cancerous. Thus, just because a person has these symptoms, it does not in any way provide a mesothelioma diagnosis.
Third, many types of tumors can exist in the serous cavities that are not mesothelioma. These other types of tumors can be non cancerous, or benign, that originate in the tissues of the serous membranes, other than the mesothelium. Or they can be tumors that have migrated from other organs with cancerous growths due to metastases.
Mesothelioma and Imaging Technologies
X-rays and other types of imaging technologies can be used to detect tumors or effusion (build up of fluid) in the body, including mesothelioma detection. A growth in the chest cavity will show up in an X-ray or MRI analysis. But these devices cannot directly determine the type of cancer or provide a mesothelioma diagnosis. They cannot determine whether the tumor is mesothelioma or originates from some other source.

Positron emission tomography (PET) is a type of diagnostic imaging scan that is used for malignant mesothelioma detection. PET scans use the emission of positrons (tiny particles that are emitted from radioactive substances) for the purpose of radiation detection.
Some medical professionals are of the impression that PET scans are the most effective method through which to definitively verify a case of mesothelioma. While they believe that standard imaging techniques like x-rays and MRIs should continue to play a role in diagnosing the disease, it is felt that positron emission tomography is becoming an increasingly valuable tool in the staging and typing of the latent asbestos cancer.
Diagnostic Surgery – Biopsy
To provide a mesothelioma diagnosis, a biopsy is needed. This biopsy then undergoes what is called diagnostic histopathology. Histopathology is a technique where the cells from the tumor are viewed under a high-powered microscope, or electron microscopy. Electron microscopy is considered the gold standard for evaluating tumor material from a biopsy. It is a highly advanced microscope that allows viewing of the tiniest elements of cell tissue.
For mesothelioma diagnosis, a pathologist (a doctor who specializes in disease detection) places the tumor cells in the electron microscope and then views the structure of the individual cells. The mesothelioma cells have a specific shape and pattern, and this allows them to be identified by a very keen pathologist. But mesothelioma cells also look similar to other types of cancer cells, such as adenocarcinoma cells, and this can make the pathologist’s job very difficult. Even with the electron microscope, the different types of mesothelioma cells can be hard to recognize. The three types of cells are epithelioid mesothelioma cancer cells, which are tubular in shape, sarcomatoid mesothelioma cancer cells, which are oval and irregularly shaped, and biphasic mesothelioma cancer cells, which are a combination of shapes. These cells can be confused with other types of cancer cells.
New Methods For Mesothelioma Detection
Due to this diagnostic confusion, much research is underway to find new methods for diagnosis. One method is to evaluate the types of compounds generated by the mesothelioma cancer cells. This is called histochemistry. Histochemical reactions have long been used to distinguish between mesothelial and other types of tumor cells. For example, mesothelial cells are known to produce specific types of carbohydrate compounds. Unfortunately, other types of cells in the body also produce these compounds.
Immunochemistry is also being used to detect mesothelioma. This area of study evaluates the presence of antibodies in the body. Certain types of antibodies are known to be associated with certain types of cancer. But mesothelial cells have no specific types of antibodies that can provide a “positive” marker. Consequently, immunochemistry allows the doctor to “eliminate” the other cancers, but does not indicate the presence of mesothelioma. These techniques offer insight into the disease and may help eliminate other diseases, but none can directly detect mesothelioma.
New Blood Tests for Mesothelioma Detection
SMR Protein: Recently, because of the difficulty in diagnosing malignant mesothelioma, research has concentrated on finding new ways to detect the presence of the disease. Researchers in Australia have found that a certain protein, called SMR or Soluble Mesothelin Related protein, is elevated in patients with mesothelioma. These researchers have suggested that a test for the presence of SMR in the blood could represent a useful marker for the diagnosis and disease progression. They feel that such a diagnosis tool could lead to earlier detection, and thus more effective treatment.
One of the most striking findings of their research was that several asbestos-exposed persons who tested positive for SMR were diagnosed with mesothelioma within three years. They suggested that evaluation of SMR may help to identify persons at risk for this deadly disease. Also, they found that SMR levels increase as mesothelioma progresses, suggesting that SMR evaluation could be used to track the progression of the disease and the effectiveness of treatment
Osteopontin Glycoprotein: In an effort to produce the first early-detection test to screen for malignant mesothelioma, researchers at Wayne State University have been studying the possible link between mesothelioma development and levels of a glycoprotein called osteopontin. Early clinical study findings of 190 patients have demonstrated a link between high levels of osteopontin and the development of malignant pleural mesothelioma.
Although the results are being viewed as preliminary, there is a great deal of excitement surrounding the potential of a blood test capable of screening for mesothelioma in its earliest stages. While there is no known cure for malignant mesothelioma, research is ongoing and certain successes have already been realized in terms of extending survival time beyond the one to two year post-diagnosis average. It is hoped that if mesothelioma specialists have more time through which to conduct treatment on a lesser developed form of the asbestos cancer, the greater a patient’s chance at potential survival.
Despite the fact that the preliminary results of the osteopontin blood test clinical trial have been met with some controversy, the National Cancer Institute (NCI) continues to sponsor additional study.
Tell Your Doctor About Asbestos Exposure
If you or a loved one has been exposed to asbestos, even if it was in the distant past, it is very important that you inform your doctor. One reason why mesothelioma is such a deadly disease is that it is detected late in the disease process. If your doctor knows of the exposure, he or she may be more aware of your symptoms or other health issues that could be used for early detection.

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What is mesothelioma?

Mesothelioma is cancer of the mesothelium. Like most cancers, mesothelioma involves the abnormal dividing of cells of a particular part of the body — in this case, the mesothelium. Mesothelioma is so deadly because it remains dormant for many years and then begins to rapidly expand. The cancer then begins to invade and damage nearby tissue, including the vital organs.

What is the mesothelium?

Many of the internal organs of the body are protected by a membrane called the mesothelium. This membrane actually consists of two layers of cells. The inner layer surrounds the organs, and the second is a sac surrounding the inner layer. When organs within this membrane must move, expand or contract — such as the heart, lungs, bladder, and so on, they are able to do so because the mesothelium produces a lubricating fluid between the two layers.

Mesothelioma most often begins in the pleura or peritoneum. The pleura surrounds the lungs and covers the chest cavity. The peritoneum covers most of the organs in the abdominal cavity. Other mesothelium tissue is also vulnerable to mesothelioma. These include the pericardium that surrounds and protects the heart; the tunica vaginalis testic which surrounds the internal male reproductive organs; and the tunica serosa uteri which is the membrane covering the internal reproductive organs in women.

Who is at greatest risk to develop mesothelioma?

Mesothelioma has a very specific cause - exposure to asbestos. During the first half of the previous century, right up until the mid 1970s asbestos was an important material used to insulate buildings, machines, heavy equipment, and a broad range of commercial applications. Because it was plentiful and inexpensive to mine, asbestos was used in many building products such as home insulation, floor, ceiling and roof tiles. It was also used in commonly found commercial products such as brake linings and pipe insulation.

This meant that millions of people were coming in contact with asbestos on a daily basis. And since the effects of exposure to asbestos fibre often do not become apparent for 30 or 40 years after prolonged exposure, companies and health officials were slow to recognize the dangers of asbestos. As a result, shipyard workers, men and women working in asbestos mines and mills, workers producing asbestos products, workers in the heating and construction industries, and virtually all other tradespeople were exposed to asbestos fibres for extended periods of time.

Today it is understood that anyone working with or near asbestos has an increased risk of developing mesothelioma, so there are strictly controlled limits of exposure in the work place. But since the dormancy period of mesothelioma can often be 30 or 40 years, there are millions of workers who are at risk because of their exposure in the decades before the safety controls were put in place.

What are the symptoms of mesothelioma?

Pleural mesothelioma - cancer of the pleura or lung lining - causes shortness of breath or chronic coughing. Other symptoms of pleural mesothelioma may include chest pain, chronic coughing, shortness of breath, fatigue, wheezing, hoarseness, weight loss, or blood in the phlegm from the lungs when coughing.

Peritoneal mesothelioma affects the lining around the stomach and intestines and is usually just as dangerous. Symptoms of peritoneal mesothelioma include pain or swelling in the abdomen, weight loss, bowel obstruction, anemia, and fever.

Many of the symptoms of mesothelioma can easily be mistaken for allergies or a common cold. Mesothelioma is often discovered when patients think they have one of these other common illnesses.

How Serious is Mesothelioma?

By the time most infected people become aware they have mesothelioma, it is no longer dormant and becomes extremely aggressive. In its active phase, mesothelioma can travel quickly, and is almost impossible to stop. There are treatments used to keep the patient comfortable, but there is currently no cure for mesothelioma. As many as 75% of those who develop the disease will lose their life within one year. The remainder may last for up to an additional six months.

This makes it extremely important to detect the disease before it enters its active phase.

How is mesothelioma diagnosed?

Mesothelioma is often not diagnosed until it reaches an advanced stage. This is because of its long dormancy period, and because once it becomes active the initial symptoms are similar to much more comman and less dangerous sicknesses such as colds or the flu. If a patient has a history of exposure to asbestos, then a complete physical examination is advised. This would normally include x-rays of the chest or abdomen and lung function tests. It might also include a CT (or CAT) scan or an MRI. Both of these tests give detailed pictures of areas inside the body.

If these tests indicate the probability of mesothelioma, then it is necessary to perform a biopsy to confirm the diagnosis. Doing a biopsy involves an oncology specialist taking a small sample of affected tissue and examining it under a microscope for signs of malignancy. Depending on the location of the affected tissue, doing a biopsy can be a relatively traightforward procedure. It normally involves the insertion of a small instrument into the suspect cavity. These surgical devices have both viewing and sample taking capabilities. So the oncologist or surgeon can look at the cavity from the inside, and then take tissue samples from different areas.

If mesothelioma is discovered, the initial tests are followed up with what is called “staging”. This involves more tests to determine how far the disease has spread.

How is mesothelioma treated?

Standard treatments include the normal options available to cancer patients: surgery, radiation therapy, and chemotherapy. Sometimes, these treatments are combined. If the mesothelioma is discovered at an early enough stage these treatments can sometimes be effective.

Among the treatments that are used in order to reduce the effects of the disease are oxygen, postural drainage and pain killers. Many alternative treatment methods are also being tested, including attempts to strengthen the body’s immune system. Gene therapy is also being tested in an attempt to attack the problem at the DNA level. Other treatments being tried and tested include homeopathy, herbs and acupuncture. Unfortunately none of these have been found to be very effective once the disease reaches its aggressive stage.

As with all cancers, early detection is the best defense against mesothelioma. Anyone who has been exposed to asbestos should be alert for symptoms and contact a doctor immediately. Detecting mesothelioma at the earliest stage possible greatly increases the chances of beating the disease.

About The Author

Rick Hendershot

For more information about Mesothelioma visit http://www.mesotheliomaadvisors.com ==> For more articles and reports about mesothelioma see http://www.mesotheliomaadvisors.com/reports.html ==> Rick Hendershot is a writer and online publisher. For publishing and promotion opportunities see http://www.linknet-blogs.com.

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