Archive for the tag 'fibrosis'

Medical mesothelioma diagnosis

by Mr.sc. Adam Vrancic

Medical thoracoscopy in the diagnosis of unexplained pleural effusion.

Respirology 1998 Jun;3(2):77-80

Wilsher ML, Veale AG

Respiratory Services, Green Lane Hospital, Auckland, New Zealand.

Approximately 20% of pleural effusions remain without an established aetiology after evaluation. Thoracoscopy has a very high sensitivity for the diagnosis of both benign and malignant diseases and greatly increases the diagnostic yield for pleural effusion. We sought to evaluate the diagnostic yield and safety of medical thoracoscopy at this institution.

The records of all patients undergoing medical thoracoscopy for the evaluation of undiagnosed pleural effusion between 1990 and 1996 were reviewed. The procedure was performed under local anaesthesia with sedation using a Stortz rigid thoracoscope. Fifty-eight patients had thoracoscopy, most having had two (range: 1-6) non-diagnostic pleural aspirations and biopsies of the pleura. Nineteen patients were found to have mesothelioma and nine metastatic malignancy. Three patients were considered likely to have tuberculous pleural disease, six had asbestos related benign pleural fibrosis and three post-cardiotomy syndrome.

There was one chylous effusion of uncertain aetiology, one posttraumatic and two other benign effusions, both of which resolved without clear aetiology. On seven occasions the pleural space could not be adequately accessed, but none of these patients had prior computerized tomography (CT) or ultrasound of the pleural space. There were five false negative diagnoses of malignancy, but no false positives.

The diagnostic sensitivity for pleural malignancy was 85% and specificity 100%. There were no major complications, but four patients had late tumour seeding at the thoracoscopy site. Medical thoracoscopy is a safe procedure with a high diagnostic yield. Pre-operative evaluation of the pleural collection using ultrasound or CT increases the likelihood of successful access to the pleural space and may increase diagnostic yield.

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The industries with a high risk for exposure to asbestos

Asbestos is a mineral, which is amazing natural fibrous. It is fire-resistant and resistant to chemicals very strong. It can be easily done in the fabric, clothing flame retardants. Although such a substance, it is very dangerous for the employees and workers who work with her. It leads to various diseases such as asbestosis, fibrosis, and even asbestos warts, cancer. The mesothelioma, a deadly disease that is the worst of all diseases caused by asbestos. For this reason, the use of asbestos, the mining and the production has been banned in many countries, a few decades. But, there are still many countries, such as India and China, are not yet that the ban of asbestos. Even those of the developed countries which have banned asbestos, are still to be collected, the problems of asbestos exposure. That is because the diseases caused by asbestos exposure have a long latency period. For example, mesothelioma, can still grow to 40 years after asbestos exposure.

One problem with asbestos is, what if it is used and produced a lot of asbestos dust and asbestos fibers are released into the atmosphere. Because they are easily and invisibly, the workers breathe easy. The problem comes later, that the fibers are very harmful when inhaled. For example, if the asbestos fibers are in contact with the mésothélium fed, they react negatively to the cells, the tumors. The tumors are in the parts of the body, such as lungs, heart and abdomen. This disease is also known as mesothelioma. These tumors can spread in the body and finally leads to bottlenecks.

The following industries have an increased risk of asbestos exposure:

The entrepreneurs or workers in the construction industry:

Since asbestos is very strong, flexible and fire protection, is a material that strongly preferred, in all types of construction work. In a way, or in any form, asbestos is in the colours, glue, tubes, slides, and so forth. Not only the employees but also the residents, the children of the schools in the schools, in the offices and all the other agencies with a threat from asbestos.

Fire brigade:

Yesterday, in the years, the fire brigade were clothes from tissues with asbestos. These clothes fire, has led to various risks to health from exposure to asbestos. Even now, when old buildings collapse because of the fire, the fire brigade, the asbestos.

Power Plants:

The boilers and generators of the power plants are mostly lined with asbestos. This is necessary for the protection from the heat and sudden fires.

Vehicle Mechanic:

Machines work with the brake pads and clutches, which contain asbestos. So they get the asbestos. Even if the asbestos is now banned, the old vehicles containing asbestos at those parts.

Minors:

Minerals such as vermiculite, which contain asbestos and talc. It is not just the few, but the few of asbestos minerals will be symptoms caused by asbestos.

Builder:

Most components of ships such as hot-water pipes, the incineration plant in insulation, boilers and steam pipes, which contain asbestos. Since asbestos is the evidence of fire, chemical-proof, robust and flexible, it is in a popular vessel components. Therefore, the workers of the shipyards have an increased risk of developing diseases associated with asbestos, such as mesothelioma. During the Second World War, there was a widespread use of asbestos in the United States just over 4 million people worked in the shipyards. From the revision and the destruction of the old ships are also many of asbestos dust and is therefore very dangerous.

Railroads:

Just as the automobile manufacturers and ships, trains also have the use of asbestos in the steam pipes, boilers, seals, clutches and brakes.

Steel Mills:

Asbestos, in the heat insulation of the substances used in the steel mills.

The oil refineries:

It is expected that in many regions of the oil refineries also contain asbestos, such as mesothelioma is very high among employees in the refinery.

Well, we see a precise knowledge about how asbestos affects the different areas of work, which is not convincing. It is important to ensure, and to be vigilant to prevent asbestos exposure.

Occupational Mesothelioma

Asbestos is a mineral, which is amazing, with high strength and heat. Thus, he was frequently used in the reproduction of fires in buildings and ships. To meet these requirements, various mining companies began to asbestos in large quantities. The enormous profits made by this industry, the owners neglect potential dangers to the health of employees. At the beginning of the year 1900 itself, the researchers in medicine have noted that asbestos is harmful to the health. A variety of lung diseases, including mesothelioma and lung cancer, which are by asbestos reporting agents.

The increasing use of asbestos has a strong effect of fibrosis, asbestosis and other diseases, the people who have worked in industries that are of asbestos for 20 years or older are the most vulnerable More mergers diseases in connection with asbestos. But the people who inhaled a very small amount is very low for a period can succumb to this disease, the rich industrial eyes on this big problem. In many, the garment workers have asbestos fibres and they crossed to the fibers and disease to their families and neighbors.

Precautionary measures:

The best protection measures taken by the workers of the asbestos industry must wear clothes which they protects the fibers. Therefore, an attempt should be made to dust and pollution in these areas. The workers should wash and change clothes before you leave the house.

Mesothelioma caused by exposure to asbestos fibers, is a terrible disease in which the cells of the mésothélium rapidly proliferate and for the facilities nearby. The mesothelioma cancer cells can or not cancer cells. If it is cancer patients, it is known as a form of malignant mesothelioma, and if it is not malignant, it is the benign form. The pain and suffering of the patients are concerned, is too terrible to describe. The chemotherapy, surgery and a constant control for patients during their life. Patients receive analgesics to help them endure the terrible pain.

The link between asbestos fibers and the disease has been discovered that in the years 1930. But it is only in the years 1940, mesothelioma has been sent to the exhibition in the asbestos fibers • The main reason that the harmful effects of asbestos was not discovered because of the time gap between exposure and the occurrence of the disease. Sometimes it can even be from 35 to 40 years. Many workers transition thirty-six thousand jobs until that time, and they are not capable, their fate to link asbestos exposure.

The industrial and fear that the provision of security and halt the production, have tried to prevent the continuation of research in these areas. In addition, they include the results of research and misrepresentation and conclusions to argue. But today in many countries, the harmful effects of asbestos and have forbidden him, for various applications. Some countries, such as India and China no measures taken to the considerable burden of asbestos and for the protection of employees.

To protect the claws, the innocent mesothelioma is the responsibility of the governments of individual countries. They should inform the general public about the hazards of asbestos and to check whether all industries follow safety.