An overview of the options for the treatment of Mesothelioma
Mesothelioma Treatment options depend on many factors such as time, place and the age of patients and wishes. Important external factors to take into account the much experience with the oncologists at mesothelioma, and if so, whether a city-rural area to be transferred to a big city or for the aggressive palliative care. Survival rate of patients is determined to up to one year, while some major centres were of a cancer of the life expectancy after diagnosis, so as to be that five years longer. Screening By imaging tests allow doctors to see a photo on the side of the cancer. These tests can also use the X-ray computed tomography (CT) or MRI (magnetic resonance imaging). New tool for early detection: The test Mesomark The Food and Drug Administration has just the (January 2007), the first test for the in-vitro mesothelioma. Mesomark The test, developed by Fujirebio Diagnostics is in the patients with epithelioid biphasic mesothelioma or by a simple blood test. The test measures proteins in the blood, changes in the volume of the patient’s tumor is an important factor for the monitoring of the patient and the response to therapy. Modern Art treatment Surgery, the removal of the entire lung and in a part of the edition of the chest, the diaphragm and the part of the bag, which surrounds the core. Thoracoscopie is the insertion of an endoscope, which is a small narrow tube with a small cameria pleural fibrosis in the cave, situated directly on the tumor. Pathologiste, a biopsy, a tissue. Often chemical pleurodesis (emptying the liquid in the space intrapleurale), during the same procedure. Médiastinoscopie, another type of surgery is sometimes used for the measure from the stage of the disease, when enlarged nodes are using imaging techniques. Laproscopy mesothelioma in the techniques of imaging in patients indicate that the tumor invaded by the diaphragm. This information is important in assessing a patient potential for pleurectomy or extrapleuralen lung resection. Radiation Therapy (with high doses of X-rays or other high-energy radiation for cancer cells. Irradiation - Although the mesothelioma tumours are very resistant to radiation therapy, sometimes, these treatments to alleviate the symptoms that arise from the growth of tumors, such as the blocking of a main blood vessel problem. Radiation therapy is generally at the opening of the chest drain sites to prevent the growth of tumors along the paths in the chest wall. Chemotherapy - is used to prevent the cancer cells to grow and divide. Immunotherapy: intraopérative Intrapéritonéale heated chemotherapy is necessary to deprive the tumor as much as possible, followed by the direct administration of a heated between (40 and 48 ° C), chemotherapy, in the abdomen, while 60 to 120 minutes, then Abgetropfte. Palliative care procedures Pleuropéritonéale shunt is a procedure in which a catheter under the skin of pleural mesothelioma in the abdominal cavity. This procedure raises concern that the catheter may cause damage by anchoring himself in the abdomen. Pleurectomy a palliative procedure, if further surgery is not an option. The procedure can not effectively remove tumors. It is regarded as the most effective means to control the pleural effusion (water storage), in cases where the expansion of the lungs is by mesothelioma. Potentially curative These procedures are “intent” healing. Pleurectomy / Peel, usually in patients with early stage disease pleural mesothelioma (stage I and stage II select), and tried all gross tumor. Extrapleural Pneumonectomy for surgery is the removal of a diseased lung, a portion of the Pericardium a part of the membrane and a part of the parietal pleura. This type of surgery is often used to a clever and traditional mesothelioma in combination with chemotherapy and / or radiation therapy, gene therapy, immunotherapy, or photodynamic therapy. Cytoreductive Surgery removed tumors visible in the abdominal cavity. The rest of the cancer cells by intra-peritoneal hypertermiques (heated) chemotherapy (IPHC), then delivered the abdominal cavity. New treatments or experimental Gene Therapy: The best-known gene, called the p53 tumor. When this gene is damaged or missing, or genes, oncogenes cancer proliferate in a normal pace. The main axis of gene therapy for mesothelioma is a virus injected, has been changed, in the laboratory. The virus is in the room pleural mesothelioma in the chest, where the mesothelioma developed to be an attempt to kill cancer cells. Vaccine or drug therapy The mesothelioma patients have a high vascular endothelial growth factor (VEGF), a chemical in the blood vessels, that the people of other types of cancer. The experiments are currently under way to check whether the VEGF can be blocked, making the vehicles of growth of blood vessels pull mesothelioma tumors. Bevacizumab is a vaccine against the drug currently in use. A process has recently declared that the drug increases the chances of survival for patients with lung cancer. An American Phase 2 bevacizumab procedures tested to mesothelioma, in combination with chemotherapy drugs. Bevacizumab is still in the testing phase, and much more important process are necessary before we know it in the treatment of mesothelioma and other types of cancer. The photodynamic therapy (PDT) In photodynamic therapy drug called a photosensitising injection into the bloodstream and into the cells of the body through which the light-sensitive cells. If the patient is in the laser light, the cells. PDT is used in combination with surgery for the treatment of patients in the early stages of mesothelioma. PDT is in the stages of the proceedings and very experimental. The clinical trials and election law The clinical studies of the research with the help of an investigation of individuals affected by cancer. The National Cancer Institute says that the purpose of most clinical trials are designed to test new drugs against cancer or new methods for diagnosis, prevention or early detection of cancer. The conditions for the approval for clinical trials is not the same, each study contains specific guidelines for participation. Some procedures allow for the participation of other treatments have failed, while others require that the patient is not treated. The choice of a clinical trial may only after a medical consultation. Examinations for the Prevention - ways to reduce the risk or the likelihood of cancer to develop. Most tests are conducted on the prevention, in which healthy people who had no cancer. These tests, drugs, vitamins or diet to reduce cancer risk. Some procedures are interviews with people who have cancer, and want to prevent the return of cancer (Relapse), or the risk of developing a new type of cancer. Screening Trial - ways to detect cancer. They are often carried out to determine whether the cancer before finding the causes of the symptoms reduces the chances of dying of the disease. These procedures are people who show no signs of cancer. Diagnosis Cancer Trials - develops new tests or scans The trials for the treatment - studies of new drugs or combinations of drugs, new treatment options, and new ways of processing Quality of life processes explore how the comfort and quality of life of patients with cancer and survivors of cancer. These tests can be opportunities for the people who are suffering from nausea, vomiting, sleep disturbances, depression, or adverse reactions, cancer or treatment. Trials Genetics Study - sometimes are part of another clinical trial of cancer. The genetic component of the negotiations may affect the way can influence the genetic detection, diagnosis, or a response to a therapy against cancer. The clinical studies are in 4 phases: The phase 1 of the examination, if the attempt to treat drug is safe or harmful, and the efforts to establish the correct dosage. Phase 2 trials check the effectiveness of the treatment. Phase 3 tests to examine a new treatment against the current standard therapy. If it leads to better results, it could be the new standard treatment. Phase 4 trials are after a drug was approved. They collect information on the side effects of the safety and the long-term risks and benefits of a drug. The research is underway, the possibilities for improving the treatment of Mesothelioma, but clinical trials are not all in new and better treatments. After the examination, he discovered that the treatment in the test does not work, or it is the worst side effect, the existing forms of treatment. But for the researchers and doctors, and at the end for the patients it is important that this research is in progress.