Archive for the tag 'tumors'

Circulating Tumor Cells Reveal Insights Into Lung Cancers - Washington Post


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Circulating Tumor Cells Reveal Insights Into Lung Cancers
Washington Post - Jul 2, 2008
By Amanda Gardner WEDNESDAY, July 2 (HealthDay News) — A new technique for finding and analyzing stray cancer cells in the blood of lung cancer patients may make it possible for doctors to one day not only determine the genetic "signature" of
New test may help doctors track tumors in 'real time' USA Today
Doctors extract cancer cells from blood sample Reuters
International Herald Tribune - HealthNews - Food Consumer - InjuryBoard.com
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Mesothelioma Survivors in Mesothelioma Symptoms

Mesothelioma symptoms are not specific to the illness, i.e., many are the Mesothelioma symptoms the same for other medical problems. Also most studies show that Mesothelioma can occurring as much as to 30 to 40 years after load by asbestos. So if a Mesothelioma symptoms arises, many Mesothelioma patients do not know that the symptoms, which experience her are connected with somewhat, which happened much early in its lives. In the reality only a brief period of the asbestos exposure, as little as some months, can cause the conditions for an illness, which breaks out many later in the life.

Mesothelioma affects the fodder of the different vacates in the body. Over time the growth cancerous of the tumors arranges this fabric to extend and seize liquid. The presence of the surplus liquid is usual, which arranges the symptoms to arise. The symptoms of the illness depend also on the position of the tumors.

Do you know more about Mesothelioma Symptoms? Tell me if you know by putting your ideas below..

The Main Types Of Malignant Mesothelioma Cancer

By Husseiny Ahmed

What is mesothelioma? This name refers to a very rare type of cancer that has some thousands of cases on all over the world. This type on cancer is caused by inhalation of Asbestos. Asbestos are some materials used in construction manufacturers.

There are four types of mesothelioma cancer, three types of them are very dangerous and are very hard to treat, there three types are Pleural Mesothelioma “Tumors develop in lung lining”, the second dangerous type is Peritoneal Mesothelioma “Tumors develop on Peritoneum, the outer membrane of the internal organs in the abdominal cavity, the third dangerous type is Pericardial Mesothelioma “Tumors develop in the sac that contain the heart”. The fourth type is Benign Mesothelioma and this type is not dangerous.

Pleural Mesothelioma is the most common type of that cancer, the most patients of that cancer are diagnosed as victims. The main reason for this disease is the inhalation of Asbestos, these Asbestos was used at construction manufacturers especially the cement manufacturing companies.

In fact, they can make a law suite to have their compensation rights from the manufacturing companies that let them exposure to Asbestos. the settlement in such cases can reach millions of dollars. There are people can help victims to get their rights and there are many lawyers specify in such settlements.

It is less common than pleural mesothelioma but it is more dangerous. In this case of cancer, tumors develop in the peritoneum, if you don’t know what is peritoneum exactly, Peritoneum is the outer line surrounds the internal organs in abdominal cavity.

Pericardial Mesothelioma, the least common type of that cancer, in this case the tumors develop in the heart lining or Pericardium.

For more information, please visit Mesothelioma Activists Site, you may also visit Pleural Mesothelioma Page and Peritoneal Mesothelioma Page find more information.

Fighting Mesothelioma Cancer With Alternative Medicine

by M Nelson

Research in alternative medicine and conventional therapies to treat Mesothelioma cancer continues to be on the forefront to try and find a cure for this disease. Until an alternative is discovered and shows promise, conventional drugs and therapies such as Alimta and other chemotherapy drugs, surgery to remove tumors, and radiation therapy will be used to slow the cancer growth.

In addition to conventional treatments, a number of therapies from alternative medicine may be able to reduce symptoms of mesothelioma. Called complementary and alternative medicine, or CAM, this diverse group of medical and health care options and practices aren’t considered to be a part of mainstream medical practice. However, that doesn’t mean that they’re ineffective. Some health care providers practice both CAM and conventional medicine, and combine the two with good results. This is referred to as integrative medicine. As much as thirty-six percent of America’s adult population are using some form of CAM. This rises to more than sixty percent if prayer and megavitamin therapy are included in the definition of alternative and complementary practices. Rates of alternative therapy use are highest among patients with serious illnesses such as mesothelioma cancer.

Some treatments offered by alternative medicine include acupuncture to relieve pain following surgery for tumor removal, ginger to treat the nausea and vomiting that chemotherapy causes, massage to treat pain from all kinds of cancers, and combining mistletoe extract with chemotherapy to treat tumors. Immunotherapy, also called biological therapy, is also becoming more common. In this therapy, substances called biological response modifiers are used to improve the immune system’s ability to recognize and destroy cancer cells, as well as to fight off other diseases.

Photodynamic therapy uses a drug that sensitizes tissues to light, then destroys cancerous cells by exposing them to a laser set to a specific frequency. Gene therapy is a new, but advancing field which treats potentially fatal diseases by modifying an individual’s genes therapeutically. Herbal medicines, traditional practices from countries such as China and Japan, and spiritual treatments are also used in CAM. Not all of these therapies have the ability to affect mesothelioma directly, and their effects will tend to vary by patient. However, they can be a big help in managing symptoms and side effects while using conventional treatments.

Those who are interested in using complementary or alternative medicine in their cancer treatment should ask their health care providers. It’s important to get the answers to a few questions when considering any therapy, whether alternative or conventional. Information such as the expected benefits of the therapy versus the risks, the potential side effects, and, in the case of alternative or complementary treatments, whether the therapy will interfere with treatments you’re already undergoing are helpful. If the therapy is part of a clinical trial, find out who the sponsor is. Many alternative therapies aren’t covered fully by health insurance. Some aren’t covered at all. It’s important to find out before beginning a CAM therapy whether or not your insurance will pay for it. A good place to start finding out about your options is the NCCAM website at http://nccam.nih.gov. From there, you’ll be able to get the information to decide what therapies, both conventional and alternative, are right for you.

About the Author
From personal research Maria Nelson provides an online research tool for cancer patients; with an emphasis on Mesothelioma cancer. Find resources to specialized cancer centers, doctors and a Mesothelioma attorneys directory for legal consideration.

Medical view of mesothelioma

by Archana Sarat

Medical View of Mesothelioma

More than 8 million people have been exposed to asbestos and are at risk of succumbing to mesothelioma. Mesothelioma is caused when the mesothelium cells start to divide rapidly leading to cancer. The only known cause of mesothelioma is exposure to asbestos fibers. The disease has a very long latency period, sometimes even around 60 years. The disease has no known cure and death becomes inevitable.

It is also very hard to correctly diagnose the disease in the early stages, as the symptoms of the disease are similar to other non-malignant diseases like pneumonia. The asbestos fiber, which is light and invisible, is released during mining and manufacture of asbestos. It is inhaled easily through nose and mouth and affects the mesothelium lining of the body part that it comes into contact with. This sets off the mesothelium cells rapid division operation, resulting in tumors. The mesothelium lining can be found in the organs like lungs, abdomen and heart.

Depending on this, mesothelioma can be classified into three categories: § Pleural mesothelioma, which affects the lungs, § Peritoneal mesothelioma, which affects the abdomen, and § Pericardial mesothelioma, which affects the heart.

Due to the long latency period of the disease, people who have worked in asbestos-related factories in their youth may contract the disease in their old age during or after retirement. Many of them may have shifted many jobs by this time and they do not relate their condition to asbestos exposure. Thus, they do not consider mesothelioma as an occupational disease. They face huge sorrow at having to part with their loved ones in such a tragic way.

Life of Jack Daws

Jack Daws was working as a tutor in the rural regions of Pennsylvania. He had a beautiful wife and a handsome son. He had what is called as a perfect family! They were always supportive and co-operative. They had enduring love and constant hope on each other.

Jack Daws loved his job as he loved kids of all ages and all sizes. He was the coach of the local soccer team during weekends. When Jack was around 55 years, he was planning on getting a retirement from the school where he tutored in another year or two.

At this crucial point of time, Jack slowly started realizing something was wrong with his health. He felt a constant pain in his chest and severe shortness of breath. He, his family and his doctor dismissed all these symptoms as a cause of aging, initially. But, slowly, his condition started to worsen. He felt as if a heavy weight has been placed on his chest. Also, he started losing weight rapidly. By now, the doctor also started sensing that something was wrong with Jack. The doctor conducted a whole lot of tests on Jack. One of the tests that were conducted was to study the fluids & cells in his lungs. After this test, the doctor felt that it appeared cancerous. Further tests followed to make the right diagnosis. It was, finally, confirmed. Jack suffered from ‘Pleural Mesothelioma’, I.e. mesothelioma affecting the lungs. Doctors felt that Jack had only another year or two of life on earth. Jack started analyzing how he contracted mesothelioma. He had never worked in any asbestos-related industries. Slowly, it dawned on Jack. Lots of construction and painting work used to be done on in his school.

Due to his long career at the school, he was constantly exposed to asbestos dust, which was used during the painting work. The company, which did the job for the school, did not take any safeguards to protect, anyone. Jack was advised to initiate proceedings against the company. The company did not disclose the dangers of asbestos and behaved in a selfish profit-oriented manner.

When Jack initiated proceeding against the company, it was found that lots of people have already sued the company for the same reason and have won their cases. Thus, the Company did not want to go into lengthy and expensive legal proceedings. They agreed to go in for an out-of-court settlement. After negotiations, the company paid Jack around a million dollars for the health damages he suffered and around two million dollars for his family-dependents. Jack underwent treatment at a cancer center. The cancer was spread all around his body and surgery was ruled out for him. Jack underwent chemotherapy and lived a life of suffering for the next two years. After that he succumbed to the disease. However, his soul will rest in peace as he has provided a safe and comfortable settlement for his loving family members.

About the Author
Archana Sarat is a freelance writer and medical researcher. Know more about mesothelioma at http://www.rarehope.com

Treat Mesothelioma Asbestos Cancer

First, I will try to inform you what the definition of Mesothelioma cancer. to understand the mesothelioma cancer, you should know that there are a type of cells that can be in the human body and called Mesothelial cells, this type of cells that build the outer membranes of some of the most important organs in the human body like lungs, heart, abdominal organs.

The types of mesothelioam may be divided to main three types, the first on that attacks the outer membrane of lungs, the second that attacks the outer membrane of heart and the third one that attacks the outer membrane of abdominal organs.

The main types of mesothelioma treatment can be divided to three options, the first option is the surgery, the second option is the radiotherapy and the third option is the chemotherapy. There are many other alternative medicine options and have a very good result when they be combined with the main option of treatments.

The surgery option can be very effective to treat mesothelioma cancer, doctors must mac an examination to discover if there are tumors in the body or not. After the examination process, doctors can remove a part of the affected organs that carries the tumors. In some cases when the tumors spread all over the organ, doctors must remove the whole organ as an very effective treatment for mesothelioma tumors.

The chemotherapy option should be occur by using some specific types of drugs that have the ability to destroy the tumors cells. The patient can take the drug directly to let them spreads throughout the blood stream and destroy the affected cells all over the body. This option of treatment can be used after the surgery to destroy any remain cancer cells. In this case, the chemotherapy treatment called “A secondary treatment”.

The radiotherapy option can be also effective by using some types of radiation that have the ability to kill the cancer cells. The radiotherapy can be used as an assistant treatment after the surgery, it can be used to kill any remain cancer cells.

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Causes of Mesothelioma Cancer

Mesothelioma cancer is the growth of malignant cells in mesothelium. This mesothelium lining covers the pleural, peritoneal and pericardial cavities. Pleura is a membrane covering the lungs and it is the most common location where mesothelioma cancer occurs also known as pleural mesothelioma. Peritoneum, the protective covering that lines the abdominal cavity may also develop malignant tumors and cause peritoneal mesothelioma.

Mesothelioma is one of the rarest cancers in the world that is caused only by exposure to asbestos. Its exposure can be direct, by inhalation of asbestos or indirect exposure in which the asbestos particles are inhaled from the clothing, hair, equipment or other articles that were previously exposed to asbestos.

Causes of Mesothelioma
Asbestos is a naturally occurring fibrous mineral that is mined in different parts of the world due to its wide utility in various industries. However, it is a deadly carcinogen too and a mojor cause of mesothelioma and asbestosis.

Asbestos fibers are known to cause cancer of the mesothelium. Asbestos is the fibrous form of several minerals and hydrous silicates of magnesium found under ground. There are 3 types of asbestos, the blue one, the while one and the brown one. Of all these 3 types, the blue one also called amphibole, long and thin in structure is more carcinogenic than white or chrysolite asbestos or the brown one known as amosite.

However, in some cases the brown asbestos has also been found to cause mesothelioma. And it is for this reason that people exposed to asbestos even for a short period are vulnerable to the disease.

Pleural Mesothelioma
Asbestos fibers are very fine and easily make their way to the lungs where they settle down in the parenchyma of the lung and penetrate the pleura that later develops malignant mesothelial plaques.

Pleura, which anchors lungs to the chest cavity, is itself a double-layered membrane. The inner layer called visceral pleura surrounds the lungs, while the outer one, known as parietal pleura, forms the lining of the pleural or chest cavity. The two pleural layers are filled with a fluid that helps them to slide over each other as we breathe. As the disease progresses, the delicate pleural membranes thicken and press the lungs. A fluid secreted by the malignant cells, pleural effusion, may also collect between visceral and parietal pleurae that causes problem in breathing and other complications.

Peritoneum Mesothelioma
The asbestos fibers may also cause cancer in the peritoneum, known as peritoneal mesothelioma. This leads to thickening of the membranes surrounding abdominal organs and collection of a fluid, ascites in the abdominal cavity making it swell.

Though it is yet not clear how peritoneal mesothelioma develops, it is believed that from lungs, the asbestos fibers are transported to abdomen and its organs by the lymphatic system or they may be deposited in the gut through saliva contaminated by the asbestos fibers.

Pericardial Mesothelioma
This is the rarest type of mesothelioma cancer that comprises of only 5% of all the mesothelioma cases. Like other types of mesothelioma cancer, pericardial mesothelioma is also caused by the inhalation of asbestos dust and fibers. The lining of the chest cavity which protects the heart is known as pericardium. It is provided with a natural fluid or mucous that provide continuous lubrication to the heart so that it can work properly and perform its functions.

As the asbestos particles settle further into the lining of the chest or pericardial, the cancer spreads in the body. It destroys the heart tissues and muscles that is very hazardous to life and proves fatal for the patient.

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Pleural Mesothelioma - The Truth and Facts About Pleural Meseothelioma

Pleural Mesothelioma represents for about 75% of all Mesothelioma cases and. The main cause for this type of cancer is the inhalation of asbestos fibers which get embedded in the lung linings, also known as the pleura. These embedded fibers will cause inflammation which will eventually lead to cancer tumors if not treated at the beginning stage.

Also, if the cancel tumors are not detected early, they can spread from the lung pleura to other vital organs which include the heart and abdomen. Pleural Mesothelioma can also invade the lymph nodes and affect the body’s blood system.

The main cause of this type of cancer is exposure to asbestos. If a person is exposed to asbestos for only a couple of months, the deadly and fine asbestos particles may lead to Pleural Mesothelioma 30 to 50 years later. The older generation especially men in their sixties or seventies are most at risk, because this was the generation that worked with the deadly material with minimal protection. Because it takes so long for this type of cancer to surface, these men are only now discovering that they have this deadly cancer. Many now are filing lawsuits against the companies who are responsible for exposing them to asbestos.

Among the symptoms associated with Pleural Mesothelioma is chest pain. However, the pain is does not come directly from the lung pleura but often appears in the shoulder or upper abdomen. Persistent coughing, shortness of breath, facial swelling, weight loss, fever and coughing up blood are the other symptoms of this type of cancer. The tumor for this type of cancer grows rapidly and enlarges the pleural space, causing this space to be filled with fluid. This is the fluid responsible for the discomfort or pain associated with the early symptoms of this cancer. Many of these symptoms are similar to diseases which are more common than this cancer and hence it is very difficult to diagnose until it is too late.

There is not proper cure available for Pleural Mesothelioma and treatment options are limited. Active research is being conducted around the globe and many pharmaceutical companies are testing new drugs to combat this cancer. Current available treatments for this cancer include chemotherapy, radiation therapy and surgery.

According to a research done on 167 patients with proven Pleural Mesothelioma, the median survival rate of patients following diagnosis was 242 days. The survival rate was also affected by the type of cancer cells, age, medical record, and lifestyle. Through this research, patients with biphasic cell types had the shortest life expectancy. The chance of survival can be drastically increased if this cancer is treated in its early stages because once it has developed and spread it is very difficult to cure.
By Ray Lam


Find out more on Pleural Mesothelioma by visiting http://raysinfo.info a popular information website that specializes in offering information about health, wealth, wisdom and also about Mesothelioma Cancer.

Mesothelioma Pain Management

Malignant mesothelioma is a disease that typically has no symptoms early in the disease process. In many cases, the asbestos exposure that caused the disease could have occurred as many as 30 to 60 years earlier. Mesothelioma starts to develop when asbestos fibers become imbedded in the lung and scar tissue forms around the asbestos fibers. But the patient does not detect the formation of the scar tissue, as it causes no perceptible pain.

As the fibrous scar tissue accumulates in large quantities and the cancerous tumors start to grow in the mesothelium, large amounts of fluid start to gather. This fluid causes much of the pain associated with mesothelioma. Chest pain due to pressure and pain during cough are directly caused by the fluid accumulation.
The growth of the tumors can also cause pain as the tumors push against the nerves and other organs. It is important that if the mesothelioma patient experiences this pain, then the doctor should be advised. There is absolutely no need to endure pain when there are remedies available to make the patient more comfortable.
Certain cancer treatments may help to relieve the pain if the tumors are removed or progression slowed. Also, the fluid can be drained to help eliminate the pressure caused by the accumulation. And there are specific pain management tools apart from the direct treatment for the cancerous tumors. The patient should ask the doctor about directly treating the pain.

Diagnosis of Mesothelioma

Malignant mesothelioma detection, like other cancers, can be accomplished with imaging equipment, such as x-ray machines. But once detected, mesothelioma diagnosis is difficult for a number of reasons. First, there is a very extended time period between the exposure to asbestos and the onset of the disease, sometimes as long as 50 to 60 years. Patients would often not think to tell their doctors about working in an asbestos-related job many years earlier.

Second, the typical symptoms of mesothelioma, shortness of breath and coughing, are also symptoms of many other types of lung problems, both cancerous and non-cancerous. Thus, just because a person has these symptoms, it does not in any way provide a mesothelioma diagnosis.
Third, many types of tumors can exist in the serous cavities that are not mesothelioma. These other types of tumors can be non cancerous, or benign, that originate in the tissues of the serous membranes, other than the mesothelium. Or they can be tumors that have migrated from other organs with cancerous growths due to metastases.
Mesothelioma and Imaging Technologies
X-rays and other types of imaging technologies can be used to detect tumors or effusion (build up of fluid) in the body, including mesothelioma detection. A growth in the chest cavity will show up in an X-ray or MRI analysis. But these devices cannot directly determine the type of cancer or provide a mesothelioma diagnosis. They cannot determine whether the tumor is mesothelioma or originates from some other source.

Positron emission tomography (PET) is a type of diagnostic imaging scan that is used for malignant mesothelioma detection. PET scans use the emission of positrons (tiny particles that are emitted from radioactive substances) for the purpose of radiation detection.
Some medical professionals are of the impression that PET scans are the most effective method through which to definitively verify a case of mesothelioma. While they believe that standard imaging techniques like x-rays and MRIs should continue to play a role in diagnosing the disease, it is felt that positron emission tomography is becoming an increasingly valuable tool in the staging and typing of the latent asbestos cancer.
Diagnostic Surgery – Biopsy
To provide a mesothelioma diagnosis, a biopsy is needed. This biopsy then undergoes what is called diagnostic histopathology. Histopathology is a technique where the cells from the tumor are viewed under a high-powered microscope, or electron microscopy. Electron microscopy is considered the gold standard for evaluating tumor material from a biopsy. It is a highly advanced microscope that allows viewing of the tiniest elements of cell tissue.
For mesothelioma diagnosis, a pathologist (a doctor who specializes in disease detection) places the tumor cells in the electron microscope and then views the structure of the individual cells. The mesothelioma cells have a specific shape and pattern, and this allows them to be identified by a very keen pathologist. But mesothelioma cells also look similar to other types of cancer cells, such as adenocarcinoma cells, and this can make the pathologist’s job very difficult. Even with the electron microscope, the different types of mesothelioma cells can be hard to recognize. The three types of cells are epithelioid mesothelioma cancer cells, which are tubular in shape, sarcomatoid mesothelioma cancer cells, which are oval and irregularly shaped, and biphasic mesothelioma cancer cells, which are a combination of shapes. These cells can be confused with other types of cancer cells.
New Methods For Mesothelioma Detection
Due to this diagnostic confusion, much research is underway to find new methods for diagnosis. One method is to evaluate the types of compounds generated by the mesothelioma cancer cells. This is called histochemistry. Histochemical reactions have long been used to distinguish between mesothelial and other types of tumor cells. For example, mesothelial cells are known to produce specific types of carbohydrate compounds. Unfortunately, other types of cells in the body also produce these compounds.
Immunochemistry is also being used to detect mesothelioma. This area of study evaluates the presence of antibodies in the body. Certain types of antibodies are known to be associated with certain types of cancer. But mesothelial cells have no specific types of antibodies that can provide a “positive” marker. Consequently, immunochemistry allows the doctor to “eliminate” the other cancers, but does not indicate the presence of mesothelioma. These techniques offer insight into the disease and may help eliminate other diseases, but none can directly detect mesothelioma.
New Blood Tests for Mesothelioma Detection
SMR Protein: Recently, because of the difficulty in diagnosing malignant mesothelioma, research has concentrated on finding new ways to detect the presence of the disease. Researchers in Australia have found that a certain protein, called SMR or Soluble Mesothelin Related protein, is elevated in patients with mesothelioma. These researchers have suggested that a test for the presence of SMR in the blood could represent a useful marker for the diagnosis and disease progression. They feel that such a diagnosis tool could lead to earlier detection, and thus more effective treatment.
One of the most striking findings of their research was that several asbestos-exposed persons who tested positive for SMR were diagnosed with mesothelioma within three years. They suggested that evaluation of SMR may help to identify persons at risk for this deadly disease. Also, they found that SMR levels increase as mesothelioma progresses, suggesting that SMR evaluation could be used to track the progression of the disease and the effectiveness of treatment
Osteopontin Glycoprotein: In an effort to produce the first early-detection test to screen for malignant mesothelioma, researchers at Wayne State University have been studying the possible link between mesothelioma development and levels of a glycoprotein called osteopontin. Early clinical study findings of 190 patients have demonstrated a link between high levels of osteopontin and the development of malignant pleural mesothelioma.
Although the results are being viewed as preliminary, there is a great deal of excitement surrounding the potential of a blood test capable of screening for mesothelioma in its earliest stages. While there is no known cure for malignant mesothelioma, research is ongoing and certain successes have already been realized in terms of extending survival time beyond the one to two year post-diagnosis average. It is hoped that if mesothelioma specialists have more time through which to conduct treatment on a lesser developed form of the asbestos cancer, the greater a patient’s chance at potential survival.
Despite the fact that the preliminary results of the osteopontin blood test clinical trial have been met with some controversy, the National Cancer Institute (NCI) continues to sponsor additional study.
Tell Your Doctor About Asbestos Exposure
If you or a loved one has been exposed to asbestos, even if it was in the distant past, it is very important that you inform your doctor. One reason why mesothelioma is such a deadly disease is that it is detected late in the disease process. If your doctor knows of the exposure, he or she may be more aware of your symptoms or other health issues that could be used for early detection.

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